Found 74 matching trials
Safety and Oversight of the Individually Tailored Treatment Approach: A Novel Pilot Study NA This study is looking at outcomes in people with advanced cancers who have ...
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Peter MacCallum Cancer Centre
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TraMel-WT: A Trial of Trametinib in Patients With Advanced Pretreated BRAFV600 Wild-type Melanoma PHASE2 This phase 2 trial will investigate the efficacy and safety of trametinib a...
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Universitair Ziekenhuis Brussel
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Dabrafenib/Trametinib, BRAF or BRAF AND MEK Pre-op With BRAF and MEK Post-op, Phase IIB, Melanoma With Brain Mets,Biomarkers and Metabolites PHASE2 This is a global, multi-centre, open-label, study of GSK2118436 conducted i...
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GSK Investigational Site
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PDR001 Combination Therapy for Radioiodine-Refractory Thyroid Cancer PHASE2 The purpose of this study is to find out whether a drug called PDR001, comb...
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Active Not Recruiting
Location
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
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Compassionate Use Program BRAF Mutation-positive Patients in the Adjuvant Treatment of Melanoma After Surgical Resection N/A The purpose of this Treatment Plan is to allow access to trametinib and dab...
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No Longer Available
Location
Multiple Locations
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Dabrafenib and Trametinib Combination as a Neoadjuvant Strategy in BRAF-positive Anaplastic Thyroid Cancer PHASE2 The aim of the study was to evaluate the effectiveness of combination thera...
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Saint-Petersburg State University (SPSU) N.I.Pirogov Clinic of High Medical Technologies
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An Open Label Study to Examine the Effects of a High-Fat Meal and Particle Size on the Pharmacokinetics of Orally Administered GSK2118436 in Subjects With BRAF Mutation Positive Tumor PHASE1 The study is designed to evaluate the effects of a high fat meal on the pha...
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GSK Investigational Site
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Pharmacokinetics of Repeat Oral Doses of Dabrafenib and the Combination of Dabrafenib and Trametinib in Chinese Subjects With Melanoma PHASE1 Present clinical study will be conducted in China to evaluate the pharmacok...
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Multiple Locations
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A Study of the Anti-PD1 Antibody PDR001, in Combination With Dabrafenib and Trametinib in Advanced Melanoma PHASE3 The purpose of this study was to evaluate safety and efficacy of the combin...
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California Cancer Associates for Research and Excellence
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Compassionate Use Program to Access Trametinib and Dabrafenib for Patients With BRAF Mutation-positive Metastatic Melanoma N/A The purpose of this Cohort Treatment Plan is to allow access to trametinib ...
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No Longer Available
Location
Multiple Locations
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